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|Method & Line||Sample & Target||Product||Package Info|
|Clinical Chemistry||Plasma,Serum||AST - GOT||Tests per Package: 944|
|Pchem Reagents||The Pchem AST-GOT Reagent Kit has been designed for use in the quantitative determination in vitro of the GOT activity in human serum or plasma. The results of the test must always be interpreted in conjunction with the clinical picture.||Code: ADA-R0200001101||Package: R1 4 x 45.5 mL; R2 4 x 5.0 mL|
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The Pchem AST-GOT Reagent Kit has been designed for use in the quantitative determination in vitro of the GOT activity in human serum or plasma. The results of the test must always be interpreted in conjunction with the clinical picture.
This kit is intended for In vitro diagnostic use only, must not be sold to the general public and the test has to be carried out by a health-care professional person.
The kit contains reagents sufficient for 944 tests.
Aspartate aminotransferase (AST/GOT) and alanine aminotransferase (ALT/GPT) belong to the group of aminotransferases or transaminases; these catalyze the reversible transformation of a-cheto-acids into aminoacids through the transfer of amino groups. AST and ALT are present in human plasma, bile, cerebrospinal fluid and saliva. The serum ALT and AST levels are increased in viral hepatitis and in other forms of hepatic disease. In spite of the fact that, in such cases, both enzymes show raised serum levels, ALT is the more specific enzyme for the diagnosis of hepatic damage. AST levels can rise in connection with cardiac or skeletal muscle damage, in addition to hepatic parenchymal tissue damage.
In the presence of 2-oxoglutarate, aspartate is transformed into oxalacetate and glutamate by the aspartate aminotransferase (AST/GPT) present in the sample. In the presence of NADH and malate-dehydrogenase (MDH), oxalacetate is transformed into malate and NAD. The consumption of NADH over a given period of time, determined at lambda 340 nm, is proportional to the GOT concentration in the test sample.
Pchem AST-GOT Reagent Kit
Reagent 1 (R1) – 4 x 45.5 mL/vial
Reagent 2 (R2) – 4 x 5.0 mL/vial