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|Method & Line||Sample & Target||Product||Package Info|
|Clinical Chemistry||Serum,Urine||CREATININE||Tests per Package: 1007|
|Pchem Reagents||The Pchem Creatinine Reagent Kit has been designed for use in the quantitative determination in vitro of the Creatinine concentration in human serum or urine. The results of the test must always be interpreted in conjunction with the clinical picture.||Code: ADA-R0200000501||Package: R1 4 x 48.5 mL; R2 6.5 mL|
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The Pchem Creatinine Reagent Kit has been designed for use in the quantitative determination in vitro of the Creatinine concentration in human serum or urine. The results of the test must always be interpreted in conjunction with the clinical picture.
This kit is intended for In vitro diagnostic use only, must not be sold to the general public and the test has to be carried out by a health-care professional person.
The kit contains reagents sufficient for 1007 tests.
Creatinine is synthesized in the kidneys, the liver and the pancreas, and is subsequently transported in the blood to other organs such as the muscles and the brain. As the production of endogenous creatinine is proportional to the muscular mass, it varies according to age and sex. The influence of the amount of meat taken in daily in the diet can be considered to be approximately 10%. In general, however, daily fluctuations in the creatinine present in the diet cause only minor variations in the daily excretion levels. High creatinine levels are seen in cases of acute or chronic renal insufficiency and in dehydration.
Jaffé (1) was the first to describe the reaction which takes place between creatinine and an alkaline picrate solution, with formation of a coloured compound. Subsequently the method used for the determination of serum creatinine was modified to improve its specificity. Creatinine reacts with alkaline picrate, forming a coloured compound which is measured at 505 nm. The rate of the colour formation is proportional to the creatinine concentration.
Pchem Creatinine Reagent Kit
Reagent 1 (R1) – 4 x 48.5 mL/vial
Reagent 2 (R2) – 4 x 6.5 mL/vial