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|Method & Line||Sample & Target||Product||Package Info|
|Clinical Chemistry||Plasma,Serum||ALBUMIN||Tests per Package: 1369|
|Pchem Reagents||The Pchem Albumin Reagent Kit has been designed for use in the quantitative determination in vitro of the Albumin concentration in human serum or plasma. The results of the test must always be interpreted in conjunction with the clinical picture.||Code: ADA-R0100000001||Package: R1 6 x 48.5 mL|
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The Pchem Albumin Reagent Kit has been designed for use in the quantitative determination in vitro of the Albumin concentration in human serum or plasma. The results of the test must always be interpreted in conjunction with the clinical picture.
This kit is intended for In vitro diagnostic use only, must not be sold to the general public and the test has to be carried out by a health-care professional person.
The kit contains reagents sufficient for 1369 tests.
Albumin is the plasma protein which is present in the largest quantities, constituting about half the total amount of proteins. It is synthesized in the hepatic parenchymal cells. The rate of synthesis is regulated primarily by COP (colloid osmotic pressure) and secondly, by the supply of protein. The normal half-life of albumin in plasma is 15-19 days. Increased albumin levels are present only in cases of acute dehydration. Decreased albumin levels are seen in numerous clinical conditions such as: analbuminemia, hepatopathic inflammation, loss in the urine, edema and ascites.
Rodkey in 1965 (1) and Hernandez in 1967 (2) described methods for the determination of albumin using Bromocresol Green (BCG). In 1972 Doumas (3) proposed a modified BCG method, establishing a reaction pH of 3.8. The Adaltis S.r.l. method is based on Doumas’s study, with a further modification to improve the linearity and stability of the final reaction colour.
In a suitable buffer solution, serum or plasma albumin binds to Bromocresol Green (BCG). The intensity of the colour which develops is directly proportional to the amount of albumin present in the sample. The presence of a tensioactive agent in the reagent increases the linearity of the reaction.
Pchem Albumin Reagent Kit
Reagent (R) – 6 x 48.5 mL/vial