IVD Reagents

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The Pchem Triglycerides Reagent Kit has been designed for use in the quantitative determination in vitro of the Triglycerides in human serum or plasma. The results of the test must always be interpreted in conjunction with the clinical picture.

This kit is intended for In vitro diagnostic use only, must not be sold to the general public and the test has to be carried out by a health-care professional person.

The kit contains reagents sufficient for 1369 tests.

Triglycerides constitute 95% of the lipids reserve in the human organism and the predominant form of glycerol esters present in the plasma. Thanks to the action of lipases and biliary salts, triglycerides are hydrolyzed into glycerol and fatty acids, and transported in the plasma by the apolipoproteins. The lipoproteins with the highest percentage of triglycerides are the chilomicrons and the very low density lipoproteins (VLDL). The combination of an increase in LDL Cholesterol and triglycerides is an aggravating factor in the risk of coronary disease. Hypertriglyceridemia is a common disease in adults and is associated with diseases such as diabetes menllitus, insulinresistance or obesity. Secondary hypertriglyceridemia on the other hand is associated with much more serious conditions such as liver and renal disease, hyperthyroidism and pancreatitis.

Glycerol released by the hydrolysis of triglycerides with lipoprotein-lipase (LPL), is transformed by glycerol-chinase (GK) to glycerol-3-phosphate which in turn is oxidased by glycerol-phosphate-oxidase (GPO) to di-hydroxyacetone-phosphate with the formation of hydrogen peroxide; this, in turn, in the presence of peroxidase (POD), reacts with ethyl-sulfopropyl-toluidine (ESPT) and 4-aminophenazone, giving rise to a coloured compound, the intensity of which is directly proportional to the triglyceride concentration in the sample.

Pchem Triglycerides Reagent Kit

Code ADA-R0100000901

Reagent (R) – 6 x 48.5 mL/vial